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Rosenau Family Research Foundation awards research grant to Dr. Chris Lee June 25, 2025

Rosenau Family Research Foundation awards research grant to Dr. Chris Lee

      Dr. Chris Lee recently received funding from the The Rosenau Family Research Foundation to support a research project titled “Molecular Characterization & Pathogenicity Assessment of Common VUS in KD”.     As Krabbe disease (KD) will be added to newborn screening programs in more states in the US, a large number of […] Read more »

Dr. Eckman and Dr. Pacheco-Quinto describe their research on Aβ42 fibrillization in synaptic endosomes in the Journal of Neuroscience November 21, 2023

Dr. Eckman and Dr. Pacheco-Quinto describe their research on Aβ42 fibrillization in synaptic endosomes in the Journal of Neuroscience

Drs. Eckman and Pacheco-Quinto share their latest research findings in a new article in the Journal of Neuroscience, titled:  Nascent Aβ42 fibrillization in synaptic endosomes precedes plaque formation in a mouse model of Alzheimer’s like β-amyloidosis. Their findings provide evidence that Aβ aggregates building up in synapses are formed locally, within synaptic endosomes, due to disruptions […] Read more »

The Legacy of Angels Foundation awards research grant to Dr. Chris Lee January 31, 2023

The Legacy of Angels Foundation awards research grant to Dr. Chris Lee

Dr. Chris Lee recently received funding from the The Legacy of Angels Foundation to continue his important research characterizing and profiling the genetic variants that cause Krabbe disease, and evaluating therapeutics that may improve outcomes for Krabbe disease patients.  Dr. Lee’s research lab has been leading discoveries in Krabbe disease research for many years.  Most […] Read more »

Dr. Memon, Dr. Griffin and Dr. Lee collaborate to study Bile Acid Metabolism in Neonates March 10, 2022

Dr. Memon, Dr. Griffin and Dr. Lee collaborate to study Bile Acid Metabolism in Neonates

Infants born prematurely often receive parenteral nutrition (PN), a life-saving source of nutrition delivered intravenously.  However, data has shown that infants fed PN long-term may be predisposed to parenteral nutrition-associated liver disease (PNALD); in part, due to alterations in bile acid metabolism.  These studies are ongoing, and are aimed at better understanding the connection between PN […] Read more »

Improving Diagnosis and Treatment for Patients with Lyme Neuroborreliosis August 22, 2021

Improving Diagnosis and Treatment for Patients with Lyme Neuroborreliosis

Dr. Eckman, in collaboration with Dr. John Halperin, lead a research team studying cerebrospinal fluid markers of Lyme disease, including Lyme neuroborreliosis, the nervous system infection associated with Lyme disease that occurs in approximately 10-15% of patients.  Their recent work was published in the journal Clinical Infectious Disease. Read more »

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